Low T? TRT Protocol Example



This is an example of what you might expect if you are diagnosed with Low T and are prescribed TRT. Remember, every person is different and your actual protocol might be as well.

TRT- Injectable Protocol

  • 100-200mg Testosterone Cypionate per week. Divided into two separate intramuscular injections
  • 250-1000iu HCG per week. Divided into two separate sub-q injections
  • 1mg of Arimidex per week. Divided into two separate doses

Note- Canadian clinical research has demonstrated that TRT by sub-q injections (under the skin injections into body fat) produces steadier testosterone levels and improves sense of well-being.

HCG is a peptide hormone that is injected sub-q to replace the lost LH hormone as the result of administering exogenous testosterone. Without hCG, the LH receptors in the testes are no longer getting activated. The results are:

  • The testes shrink. Over time for some the testes can eventually become small undifferentiated lumps of collagen. This is drug induced organ failure. The degree of shrinking varies by individual and may be more of a problem for the older men.

  • Fertility can be greatly reduced or eliminated. If hCG is not used, its use after a long time may or may not recover fertility.

  • When the testes get smaller, some feel an ache in their testes 24x7. hCG injections can eliminate that pain or avoid the whole episode.

  • When there is no LH or hCG, the scrotum pulls up tight to the body.

  • The testes are the single largest producer of the hormone pregnenolone. Pregnenolone is important for proper mental functioning, and is the precursor to all of the steroid hormones such as DHEA, testosterone, DHT, estrogen, cortisol… Injecting hCG prevents a drug induced pregnenolone deficiency and helps support the other hormones. When men are on T without hCG and then start hCG, they report a significant improvement in mood that many attribute to restored pregnenolone levels.

Arimidex is an aromatase inhibitor and is necessary when injecting exogenous testosterone to help control increases in estrogen (estrodial/E2) levels. Arimidex comes in tablet form and is taken orally.

This example protocol will all be supported by initial blood tests. For the first 6-12 months you will have more frequent blood tests until your physician has your protocol dialed in for maximum benefit. Once you have a standardized regular protocol blood test are less frequent and very few adjustments will have to be made.

It is recommended that TRT patients donate blood to control the RBC increase that injecting exogenous testosterone causes. A single RBC donation can be given every 8 weeks and a double RBC donation can be given every 16 weeks.

Expected out of pocket expense - $1200-$2800 per year. This does not include the initial start-up cost that some clinics require.

Depending on your insurance most or all of the costs of treatment can be covered.


My dad use to use the androgel shit, and now they put a small pellet in his buttcheek every so often, he said the results are way better. I told him, that no Dad, my results are way better


Another great informative post! Thanks for this brother


My RBC is slightly elevated, just slightly. For past 2 months I have been getting my back tattooed so I cannot donate. Any suggestions?


Don’t tell them about the tattoo. :wink:


Lol… Makes sense.


Occam’s Razor