Hi Everyone – I am new to the forum, and I am very thankful to have been invited! I heard elsewhere that Tamoxifen counteracts Exemestane (Aromasin). Does anyone know whether or not this is true? I’ve read all the related posts I could find, but I did not find that specific answer.
Based on my bloodwork (listed below), I am also hoping for some guidance on the dose of Exemestane I should take and (based on half life) if / when I should stop taking Tamoxifen before I start taking Exemestane.
I am currently taking 10 mg Tamoxifen twice daily (for the past six weeks) to successfully counteract tender, sore and lactating nipples. I just ordered Exemestane (Aromasin) from United. I hope this will counteract the constant bloating and massive water weight gain I experience, even on a clean diet. If it helps, I find the bloating and water retention increases with carbs.
I have no sex drive, and I also find it incredibly difficult to find any motivation to train. I go to the gym out of habit, only to find I can’t get motivated once I get there. At best I do a few exercises. At worst I go home. I’ve been going home more and more lately, which is incredibly frustrating.
I am 52 years old. I am almost 6 feet tall, and I weighed 205.4 pounds this morning. I started a prescribed TRT dosage of .5 mL / week on March 9th. After an initial round of bloodwork, my doctor increased the dosage to .7mL / week in early April. My doctor refuses to prescribe anything for high estrogen or prolactin levels. He is the second Endocrinologist I’ve worked with, and I feel I had to twist his arm to get him to prescribe testosterone for me in the first place. The first Endocrinologist said he thinks TRT will be the next “Opioid epidemic”, and he promised he would never prescribe testosterone for me, even if I have a tumor on my Pituitary gland. I paid almost $400 to hear that!
Here is the bloodwork information:
2/5 (before TRT)
Prolactin 15.5 ng/mL (Standard Range 4.0 – 15.2 ng/mL)
Estrone 42 pg/mL (Standard Range 12 – 72 pg/mL)
2/26 (before TRT)
Prolactin Serum (ICMA) 7.7 ng/mL (SR 3.0 – 18.0 ng/mL)
Monomeric Prolactin (ICMA) 7.5 ng/mL (SR 3.0 – 18.0 ng/mL)
Percent Macro prolactin 3% (SR 0 – 49%)
Sex Hormone Binding Globulin 31.7 nmol/L (SR 19.3 – 76.4 nmol/L)
Estradiol 17 Beta 6.5 pg/mL (SR 12.6 – 44.0 pg/mL)
Testosterone 112 ng/dL (Standard Range 280 – 800 ng/dL)
Testosterone Free 6.8 pg/mL (Standard Range 7.2 – 24.0 pg/mL)
3/31 (TRT started 3/9)
Prolactin 30.2 ng/ML (Standard Range 4.0 – 15.2 ng/mL)
Estradiol 17 BETA 11.5 pg/ML (Standard Range 12.6 – 44.0 pg/mL)
Testosterone 393 ng/dL (Standard Range 280 – 800 ng/dL)
Testosterone Free 15.4 pg/Ml (Standard Range 7.2 – 24.0 pg/mL)
Hematocrit 48.2% (Standard Range 39.0 – 51.0%)
I will get additional labs done in a few weeks for Testosterone total, macro prolactin, hematocrit and Estradiol 17 Beta.
I appreciate the time you have taken to read this. Thank you in advance for your help!