5 bennifits of nitric oxide and body building



Nitric oxide bennifits

  1. Erectile Dysfunction
  2. Muscle Soreness
  3. Blood Pressure
  4. Exercise Performance
  5. Diabetes
    Side Effects
    Bottom Line
    Nitric oxide is produced by nearly every type of cell in the human body and one of the most important molecules for blood vessel health.

It’s a vasodilator, meaning it relaxes the inner muscles of your blood vessels, causing the vessels to widen. In this way, nitric oxide increases blood flow and lowers blood pressure.

Supplements that increase nitric oxide in the body make up one of the most popular supplement categories today.

These supplements don’t contain nitric oxide itself. However, they contain compounds that your body can use to make nitric oxide and have been shown to provide many benefits for health and performance.

Here are 5 health and performance benefits of taking nitric oxide supplements.

  2. Help Treat Erectile Dysfunction
    Man in Suit Holding Supplement
    Erectile dysfunction (ED) is the inability to achieve or maintain an erection firm enough for sex (1).

L-citrulline is an amino acid that may help treat erectile dysfunction by increasing the production of nitric oxide (2).

Nitric oxide is needed for the muscles in the penis to relax. This relaxation allows chambers inside the penis to fill with blood so the penis becomes erect (3).

In one study, L-citrulline was found to improve erection hardness in 12 men with mild erectile dysfunction (4).

Researchers concluded that L-citrulline was less effective than prescription drugs used to treat ED, such as Viagra. Nevertheless, L-citrulline proved to be safe and well tolerated.

Two other nitric-oxide-boosting supplements have been shown to treat erectile dysfunction — the amino acid L-arginine and Pycnogenol, a plant extract from the pine tree.

In several studies, a combination of L-arginine and Pycnogenol significantly improved sexual function in men with ED (5, 6, 7, 8).

When taken together, L-arginine and Pycnogenol also appear safe (9).

Nitric oxide plays an important role in erectile function. Several supplements, including L-citrulline, L-arginine and Pycnogenol, have been shown to increase levels of nitric oxide in men with erectile dysfunction (ED).
2. May Decrease Muscle Soreness
A form of L-citrulline called citrulline malate not only increases nitric oxide production, but also decreases muscle soreness.

Muscle soreness is an uncomfortable experience that tends to occur after strenuous or unaccustomed exercise (10).

This soreness is referred to as delayed-onset muscle soreness and usually feels the strongest 24–72 hours after exercise.

In one study, 41 people were randomized to receive either 8 grams of citrulline malate or a placebo one hour before performing as many repetitions as possible on a flat barbell bench press (11).

Those given citrulline malate reported 40% less muscle soreness at 24 and 48 hours after the exercise, compared to those who took the placebo.

Citrulline malate increases nitric oxide production, which increases blood flow to active muscles. In turn, citrulline malate is thought to increase nutrient delivery and clear waste products that are related to muscle fatigue, such as lactate and ammonia (12).

However, a later study on the effects of citrulline after leg exercises did not find citrulline malate helpful for the treatment of muscle soreness (13).

One explanation for this difference in findings is that the people in the leg exercise study were given 6 grams of citrulline malate, which is 2 grams less than the previous study.

Therefore, the ability of citrulline malate to decrease muscle soreness may depend on the dose and exercise. However, more research on this is needed.

Citrulline malate is a form of L-citrulline that may help alleviate muscle soreness by increasing nitric oxide. The dose and type of exercise may affect the ability of citrulline malate to decrease muscle soreness.

  2. Lower Blood Pressure
    People with high blood pressure are thought to have an impaired ability to use nitric oxide in their bodies (14, 15).

High blood pressure occurs when the force of your blood pushing against the walls of your arteries is consistently too high.

Over time, high blood pressure can lead to health issues such as heart disease and kidney disease.

It has been shown that a diet high in fruits and vegetables decreases blood pressure and therefore lowers the risk of disease (16).

This has led researchers to test the beneficial effects of certain compounds found in fruits and vegetables on blood pressure levels.

Nitrate is a compound found in beetroot and dark leafy greens like spinach and arugula.

When you consume nitrate, your body converts it to nitric oxide, which in turn causes blood vessels to relax and dilate, lowering blood pressure.

Many studies have shown nitrate may help lower blood pressure by increasing the production of nitric oxide (17, 18, 19, 20).

One review analyzed the effects of taking nitrate supplements on blood pressure in adults (21).

Of the 13 studies analyzed, six found significant reductions in systolic blood pressure and diastolic blood pressure when participants took nitrate supplements (22).

What’s more, another review of 43 studies found participants’ systolic and diastolic blood pressures decreased by an average of 3.55 and 1.32 mm Hg, respectively, after they took nitrate supplements (23).

Like nitrates, flavonoid extracts have been shown to improve blood pressure (24, 25, 26).

Flavonoids have powerful antioxidant effects and are found in almost all fruits and vegetables (27).

Scientists believe flavonoids not only increase production of nitric oxide but also decrease its breakdown, promoting higher levels overall.

However, nitrates have more research supporting their blood-pressure-lowering effects than flavonoids do.

Vegetables and fruits contain several compounds, such as nitrate and flavonoids, that may help keep blood pressure under control by increasing nitric oxide levels.

  2. Boost Exercise Performance
    Nitric oxide is involved in many cell processes, including the widening of the blood vessels, or vasodilation. Wider blood vessels help increase the delivery of nutrients and oxygen to working muscles during exercise, thus enhancing exercise performance.

This has made nitric oxide supplements popular among athletes and recreational gym-goers.

These supplements often contain several ingredients that are said to increase nitric oxide, such as nitrate or the amino acids L-arginine and L-citrulline.

In many analyses, nitrate has been shown to improve exercise performance in cyclists, runners, swimmers and even kayakers (28, 29, 30).

On the other hand, L-arginine has not proven to be effective for improving exercise performance in many studies (31, 32, 33).

This is likely because most of the L-arginine that is ingested is metabolized or broken down before it gets a chance to reach the bloodstream, whereas L-citrulline is not (34).

For this reason, L-citrulline is more effective than L-arginine at increasing nitric oxide and therefore exercise performance (35).

Supplements intended to increase nitric oxide are commonly promoted as performance enhancers. While the performance-enhancing benefits of L-arginine are minimal, nitrate and L-citrulline may be worthwhile.

  2. May Help Manage Type 2 Diabetes
    Nitric oxide production is impaired in people with type 2 diabetes (36).

This leads to poor blood vessel health, which can lead to conditions like high blood pressure, kidney disease and heart disease over time.

Therefore, supplements that increase nitric oxide may have important implications for diabetes treatment and disease prevention.

One study found that when people with type 2 diabetes took L-arginine, their nitric oxide production increased (37).

This increase in nitric oxide also led to increased insulin sensitivity, allowing for better blood sugar control.

Another study in 144 people looked at the effects of L-arginine on preventing or delaying the progression of type 2 diabetes (38).

While L-arginine did not prevent people from developing diabetes, it did increase insulin sensitivity and improve blood sugar control.

But until more research is available, it is premature to recommend taking L-arginine supplements to treat diabetes.

People with diabetes have impaired nitric oxide production, which can lead to harmful health effects. L-arginine has been shown to improve blood sugar control in people with diabetes, but more research is needed before it can be recommended.

Side Effects
Nitric oxide supplements are generally safe when taken in appropriate amounts (39, 40, 41).

However, there are some side effects to be aware of.

L-arginine taken in doses above 10 grams can cause stomach discomfort and diarrhea (42).

Beetroot juice supplements can also turn your urine and stool a dark red color. This is a common but harmless side effect (43).

Before taking any supplements to increase nitric oxide, consult your doctor or dietitian.

Nitric oxide supplements are generally considered safe. However, there are some side effects to be aware of, including potential stomach discomfort and diarrhea, as well as dark red stool and urine.
The Bottom Line
Nitric oxide is a molecule that plays many important roles in human health.

Many supplements are claimed to increase nitric oxide in the body and provide impressive benefits for health and performance.

They usually contain ingredients like nitrate or the amino acids L-citrulline and L-arginine.

However, other supplements, such as Pycnogenol, have also been shown to increase or maintain nitric oxide levels.


Let me ask you brother: How do you know so much? I have a bachelors degree in P E ( 2 years of chemistry/biochemistry. 2 of anatomy and biology) and i don’t understand half of what you write . i swear i was not getting high in college (not yet) and i know i have average I Q (???)


I just learned from reading all these articles over the past 25 years ,Google search and muscle mags when they were good and not 90% advertiseing,I saved ever article I liked since I started 25 years ago and review them allot my friend


Thank God that you did MM because these articles are the balls! I love all this info to sharpen my bbing wits lol granted i have read most of these article along the journey over last 20+ years but rereading them and cleaning all the cob webs out of my brain has been fun! Awesome job bringing us all of these reads man :facepunch:t2:


Can’t get enough of them…many posts here have made me take different measurements, i have made changes and including lots of stuff did not know about. I hit my brother Mountain-man all the time with pm’s


MM has become a very close dear friend to me also brotha! Hes such a great dude with a heart of gold and cares so much about the best for all of his iron brothers! I consider him my big brother and part of my family not just becaus we both work for United Gear as he played a big part in getting me my 1st sponsorship but also because we talk daily he gives me great advice about everything in life from A to Z. Tons of love and respect for my brother MM!


Best nitric oxide product I ever used was Yok3d by usp labs probably 6 years back


I mixed oxide with nizagara. And there was no side effect of ED or something. But consult with your doctor at first.


I have used many products and was always happy with no myself


oh geeze…i just relized i dont have to wait for the l-arginine to come since i already have the L-citruline dl-malate 2:1

now i can make my brew!! hmmm…what would tje base beeee…expresssoooo :thinking::thinking::thinking::thinking::thinking::thinking::thinking: :rofl::rofl::rofl::rofl:


@PHD just turned me onto a supplement line that contains a patented ingredient called Vaso6. If you don’t know anything about it and understand the benefits of nitric oxide boosters you better get in the know quick because vaso6 put all those other NO boosters in the dirt combined. I honestly cannot believe I have never heard about it before and really looking forward to putting into use. A 300mg dose is 10X more effective than 7g of arginine and is shown to increase vasodilation by 50% vs. a mere 5% provided by arginine. Stack it with citrulline malate and I am sure my vascularity and muscle pumps are going to be epic.


Hell yes Bro. Awesome love hearing this. The guy that invented vaso6 is cool as hell he always comments to me and interacts on social media. The loaded af has citrulline in it :wink: my buddy shared a video with me the benefits of NO. I’ll see if I can find it.


6 full grams as a matter of fact plus 300mg of vaso6. Both the clinically effective doses of each for performance.

My wife is going to be insanely freaked. She gets the creeps at my vascularity right now. I am interested in seeing how well the muscles stay full and tight.


I did arms last night it felt like my arms were going to explode


Old video but man is it Good @SemperFi you will like this



Why in the hell wouldn’t a doctor prescribe or recommend a NO boosting supplement as a first defense?! I will tell you why… they can’t make money off a healthy person!

Great video. Thanks @PHD